Medicina

Brody's Human Pharmacology

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Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals. New to this edition Updated content throughout Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism Pharmacogenetics chapter considers genetic variations and their relationship to drug responses Section on cancer drugs revised to reflect major advances New chapter on immunological and cell-based therapies Key Features Contains all the essential aspects of pharmacology – suitable for exam preparation Full color illustrations explain important processes and color-coded boxes enhance understanding Therapeutic overviews, clinical problems and trade names – everything you need to know Self-assessment questions and further reading to reinforce learning Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life

Brody's Human Pharmacology
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Brody’s Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals. New to this edition Updated content throughout Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism Pharmacogenetics chapter considers genetic variations and their relationship to drug responses Section on cancer drugs revised to reflect major advances New chapter on immunological and cell-based therapies Key Features Contains all the essential aspects of pharmacology – suitable for exam preparation Full color illustrations explain important processes and color-coded boxes enhance understanding Therapeutic overviews, clinical problems and trade names – everything you need to know Self-assessment questions and further reading to reinforce learning Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life

Section 1 Mechanisms of Drug Action and Therapeutic Principles

1. Introduction, Terminology

Lynn Wecker

2. Pharmacodynamics: Drug Targets (Receptors, Enzymes, DNA, etc)

James Carlton Garrison II

3. Pharmacokinetics

Paul Hollenberg

4. Pharmacogenomics

Julie A. Johnson, Larisa Cavallari and Scott Mosley

5. Drug Development and Regulation

James Barrett

Section 2 Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses

6. Introduction to the Peripheral Nervous Systems and Drugs for Peripheral Disorders

Robert James Theobald Jr.

Cholinergic Drugs

7. Muscarinic Agonists and Their Clinical Uses

Frederick Ehlert

8. Muscarinic Antagonists and Their Clinical Uses

Frederick Ehlert

9. Nicotinic Agonists and Their Clinical Uses

Robert James Theobald Jr. and Lynn Wecker

10. Nicotinic Antagonists and Neuromuscular Blocking Drugs

Robert James Theobald Jr. and Lynn Wecker

Adrenergic Drugs

11. Adrenergic Agonists and Their Clinical Uses

Javier Cuevas

12. Adrenergic Antagonists and Their Clinical Uses

Javier Cuevas

Section 3 Drug Treatment for Disorders Affecting the Central Nervous System

13. Introduction to the CNS and Drugs Affecting the Brain

Lynn Wecker

Neurodegenerative Disorders

14. Drug Therapy for Alzheimer's Disease and Other Cognitive Disorders/Dementias

Steven Trent DeKosky, Meredith Wicklund and Michael Jaffee

15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson's Disease and Huntington's Disease

Juan R. Sanchez-Ramos and Briony Catlow

16. Drug Therapy for Psychoses and Bipolar Disorder

Lynn Wecker, Glenn Courrier and Glenn catalano

17. Drug Therapy for Depression and Anxiety

Lynn Wecker, Glenn Courrier and Glenn catalano

18. Stimulants and Drug Therapy for the Management of ADHD

Samba Reddy

19. Drug Therapy for Insomnia and the Hypersomnias

Lynn Wecker

20. Drug Therapy for Managing Obesity and Eating Disorders

Charles Rudick

21. Drug Therapy to Control Seizure Disorders

Michael Rogawski

22. Drug Therapy to Control Spasticity Disorders

Michael Saulino

23. Ethanol, Ethanol Dependence and Drug Therapy

Charles Whitmore and christian Hopfer

24. Other Drugs of Abuse, Addiction and Drug Therapy

Rex Philpot and Peter Kalivas

Section 4 Drug Therapy for Pain Management

25. Introduction

Susan L. Ingram

26. General Anesthetics

Jeffrey J. Pasternak and David Wetzel

27. Local Anesthetics

Joshua Edwards

28. Opioid Analgesics

Susan L. Ingram and Elena Bagley

29. Nonsteroidal Anti-inflammatory Agents and Acetaminophen

Jennelle Durnett Richardson and Jill Fehrenbacher

30. Cannabinoids

Gregory Lee Gerdeman

31. Drug Therapy for Headache

Samba Reddy

Section 5 Treatment of Inflammatory, Allergic and Immunologic Disorders

32. Drug Therapy for Rheumatoid Arthritis

Keith Elmslie

33. Drug Therapy for Gout and Hyperuricemia

Keith Elmslie

34. Histamine and Antihistamines

Kirk Dineley and Latha Malaiyandi

35. Immunosuppressants for Organ Rejection and Autoimmune Disorders

Kymberly Gowdy

Section 6 Drug Treatment for Cardiovascular Diseases

36. Introduction to The Cardiovascular System and the Regulation of Blood Pressure and Heart Rate

David A. Taylor and Abdel A. Abdel-Rahman

37. Diuretics and Drugs that Affect Volume and Electrolyte Content

Abdel A. Abdel-Rahman

38. Drugs Affecting the Renin-Angiotensin-Aldosterone System

Abdel A. Abdel-Rahman

39. Calcium Channel Blockers

Kelly Karpa

40. Vasodilators

David Anthony Tulis

41. Other Antihypertensive Drugs Acting via the Peripheral or Central Nervous Systems

David A. Taylor and Abdel A. Abdel-Rahman

42. Sodium Channel Blockers and Other Antiarrhythmic Agents

David A. Taylor

43. Treatment of Heart Failure: Cardiac Glycosides, Phosphodiesterase Inhibitors and Other Agents

Michael T. Piascik and Robert Hadley

44. Drug Therapy for Hyperlipidemias and Atherosclerotic Cardiovascular Disease

Michael T. Piascik and Robert Hadley

45. Anticoagulant, Antiplatelet and Thrombolytic Agents

Kent Vrana and Frank Herman

46. Drug Therapy for Myocardial Ischemia and Angina Pectoris

Joseph West Paul Jr.

47. Drug Therapy for Hemophilia and the Anemias

David A. Taylor

Section 7 Treatment of Endocrine Disorders

48. Introduction to Endocrine Pharmacology

Shelley Tischkau

49. Treatment of Hypothalamic and Pituitary Disorders

Shelley Tischkau

50. Treatment of Adrenalcorticosteroid Disorders

Gerald B. Call

51. Drug Therapy for the Management of Diabetes

Julio A. Copello

52. Drug Therapy for the Management of Thyroid Disorders

Shelley Tischkau

53. Calcium Regulating Hormones and Agents Affecting Bone

Jack W. Strandhoy

54. Female Hormones, Birth Control, Infertility and Drugs Affecting Uterine Function

Julia Ousterhout

55. Male Hormones and Drugs for the Treatment of Erectile Dysfunction and Benign Prostastic Hyperplasia

David Middlemas

Section 8 Chemotherapy

Infectious Diseases

56. Principles of Antimicrobial Use

Rukiyah Van Dross

57. Bacterial Cell Wall Synthesis Inhibitors

Rukiyah Van Dross

58. Inhibitors of Protein Synthesis

Rukiyah Van Dross

59. Drugs that Target DNA

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